简介内容:Thi-DPPY is a potent, orally active JAK3 inhibitor that acts on BTK (IC50: nM), JAK (IC50: nM). Thi-DPPY is anti-proliferative against HBE cells. Thi-DPPY has anti-inflammatory effects in vivo. Thi-DPPY has shown research potential in idiopathic pulmonary fibrosis (IPF).