简介内容:ODN TTAGGG (A151) is an inhibitory oligonucleotide (ODN), a TLR9, AIM2 and cGAS antagonist. oDN TTAGGG competitively inhibits AIM2 inflammasome activation by DNA and inhibits cGAS activation, exhibiting immunosuppressive activity. ODN TTAGGG can be used to study autoimmune diseases such as lupus erythematosus. oDN TTAGGG sequence: 5´-T-T-A-G-G-G-T-T-A-G-G-G-G-T-T-A-G-G-G-G-G-T-T-A-G-G-G-G-G-G-3´.