MDL-800；化合物MDL-800MDL 800|||MDL800；MDL 800|||MDL800T64529

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产品名称：MDL-800；化合物MDL-800MDL 800|||MDL800；MDL 800|||MDL800
产品型号：T64529
产品产地：中国大陆
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简介内容：SIRT6, responsible for deacetylation of histone H3 Nε-acetyl-lysines 9 (H3K9ac) and 56 (H3K56ac), is a tumor suppressor which has frequently been found to have low expression in various cancers. MDL-800 is a selective SIRT6 activator. It increased the deacetylase activity of SIRT6 by up to 22-fold and led to a global decrease in H3K9ac and H3K56ac levels in human hepatocellular carcinoma (HCC) cells. Also, it inhibited the proliferation of HCC cells via SIRT6-driven cell-cycle arrest and was eff

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原创作者：上海陶术生物科技有限公司

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