AG-012986；化合物 AG-012986AG-012986T69196 - 上海陶术生物科技有限公司

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产品名称：AG-012986；化合物 AG-012986AG-012986
产品型号：T69196
产品产地：中国大陆
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简介内容：AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition, >%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hy

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名称: AG-012986；化合物 AG-012986

描述: 化合物 AG-012986。

关键字: AG-012986 |

原创作者：上海陶术生物科技有限公司

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