AZD-1236；化合物 AZD-1236AZD-1236T69230 - 上海陶术生物科技有限公司

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产品名称：AZD-1236；化合物 AZD-1236AZD-1236
产品型号：T69230
产品产地：中国大陆
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简介内容：AZD1236 is a potent and reversible inhibitor of human MMP-9 and MMP-12 (IC50 = and , respectively), with >10-fold selectivity to MMP-2 and MMP-13 and >350-fold selectivity to other members of the enzyme family. AZD1236 activity is approximately 20 to 50-fold lower at the rat, mouse, and guinea pig orthologues. In acute models of lung injury, AZD1236 inhibited the haemorrhage and inflammation induced by instillation of human MMP-12 into rat lungs by ~80% at , and also abolished

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名称: AZD-1236；化合物 AZD-1236

描述: 化合物 AZD-1236。

关键字: AZD-1236 |

原创作者：上海陶术生物科技有限公司

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