简介内容:Roridin E inhibits the receptor tyrosine kinases FGFR3, IGF-1R, PDGFRβ, and TrkB (IC50s = , , , and 1 μM, respectively) and induces cytotoxicity in multiple breast cancer cell lines (IC50s = nM). It also inhibits proliferation in a panel of additional cancer cell lines (IC50s = < μM).