PF-05139962；化合物 PF-05139962PF-05139962T70782 - 上海陶术生物科技有限公司

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产品名称：PF-05139962；化合物 PF-05139962PF-05139962
产品型号：T70782
产品产地：中国大陆
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简介内容：PF-05139962 is a novel potent mTOR inhibitor with excellent mTOR biochemical inhibition, cellular potency, kinase selectivity and in vitro ADME properties. PF-05139962 has pS473 and pS6 cellular IC50 = 48 and 6 nM respectively. PF-05139962 has great selectivity against other receptors and kinases. No genotoxicity was observed on this compound and no more than 25% inhibiton was observed for major CYP enzymes (3A4, 1A2, 2C9, 2D6) at 3 uM. This compound has LE = and LipE up to which is in

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名称: PF-05139962；化合物 PF-05139962

描述: 化合物 PF-05139962。

关键字: PF-05139962 |

原创作者：上海陶术生物科技有限公司

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