简介内容:TC-2153 is a selective inhibitor of striatal-enriched protein tyrosine phosphatase (STEP), exhibiting psychotropic activity and low acute toxicity. This compound not only enhances the expression of brain-derived neurotropic factor (BDNF) in the brain but also reduces the mRNA levels of MAOA and 5-HT1A receptors in the midbrain. Additionally, TC-2153 inhibits 5-HT2A receptor-mediated signaling.