CBB1007 hydrochloride；化合物 CBB1007 hydrochlorideCBB1007 hydrochlorideT72388

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产品名称：CBB1007 hydrochloride；化合物 CBB1007 hydrochlorideCBB1007 hydrochloride
产品型号：T72388
产品产地：中国大陆
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简介内容：CBB1007 HCl is a cell-permeable amidino-guanidinium compound identified as a potent, reversible, and substrate-competitive inhibitor of LSD1 (IC50 = μM for hLSD1). It effectively inhibits LSD1-mediated demethylation of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM), without affecting H3K4Me3 and H3K9Me2 demethylation, nor the activities of LSD2 and JARID1A. Moreover, CBB1007 increases the levels of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM) and activates epigenetically suppressed genes CHRM4/M4-ArchR and SCN3A in

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名称: CBB1007 hydrochloride；化合物 CBB1007 hydrochloride

描述: 化合物 CBB1007 hydrochloride。

关键字: CBB1007 hydrochloride |

原创作者：上海陶术生物科技有限公司

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