简介内容:Akt1-IN-1 is a potent and selective inhibitor of Akt1, demonstrating an IC50 of nM in MIA PaCa-2 cells, indicating its high efficacy in inhibiting this specific kinase. Notably, it shows no significant teratogenicity, hepatotoxicity, or cardiotoxicity (No Observed Adverse Effect Level > 100 ?M), making it a viable candidate for anticancer research.