简介内容：ADH-6, a tripyridylamide compound, impedes the self-assembly of the aggregation-nucleating subdomain of mutant p53 DNA-binding domain (DBD). By targeting and dissociating mutant p53 aggregates in human cancer cells, ADH-6 reinstates p53´s transcriptional activity, culminating in cell cycle arrest and apoptosis, thereby holding potential for cancer research.
Customer Service
