Leriglitazone hydrochloride；化合物 Leriglitazone hydrochlorideLeriglitazone hydrochlorideT73842

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产品名称：Leriglitazone hydrochloride；化合物 Leriglitazone hydrochlorideLeriglitazone hydrochloride
产品型号：T73842
产品产地：中国大陆
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简介内容：Leriglitazone (Hydroxypioglitazone) hydrochloride, a pioglitazone metabolite, acts as a PPARγ agonist, effectively stabilizing the PPARγ activation function-2 (AF-2) co-activator binding surface to enhance co-activator binding, which results in a modest improvement in transcriptional efficacy. It binds to the PPARγ C-terminal ligand-binding domain (LBD) with a dissociation constant (K i) of μM and demonstrates transcriptional efficacy with an effective concentration (EC 50) of 680 nM [1].

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名称: Leriglitazone hydrochloride；化合物 Leriglitazone hydrochloride

描述: 化合物 Leriglitazone hydrochloride。

关键字: Leriglitazone hydrochloride |

原创作者：上海陶术生物科技有限公司

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