简介内容:HD-TAC7, a potent PROTAC HDAC degrader, exhibits IC50 values of μM, μM, and μM for HDAC1, HDAC2, and HDAC3, respectively. It effectively decreases NF-κB p65 in RAW macrophages and is utilized in research targeting inflammatory diseases such as asthma and chronic obstructive pulmonary disease (COPD) [1].