简介内容：AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC 50 of μM. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models [1] [2] .
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