PF 05089771 tosylate；化合物PF 05089771 tosylatePF 05089771 tosylateT7502

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产品名称：PF 05089771 tosylate；化合物PF 05089771 tosylatePF 05089771 tosylate
产品型号：T7502
产品产地：中国大陆
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简介内容：PF-05089771 is a voltage-gated sodium channel () blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L splice variants, respectively). It is selective for over and channels (IC50: μM), L-type calcium, and KvLQT and hERG potassium channels (IC50: ≥10 μM), as well as human and cynomolgus monkey TRPV1 receptors (IC50: 10/20 μM). PF-05089771 is also 1, 000-fold selective for half-inactivated over resting channels, and mutation o

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原创作者：上海陶术生物科技有限公司

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