简介内容:TC14012 TFA, a serum-stable derivative of T140, is a selective peptidomimetic CXCR4 antagonist with an IC50 value of nM. It also acts as a potent CXCR7 agonist, exhibiting an EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. This compound demonstrates anti-HIV and anti-cancer activities [1] [2].