简介内容:PG-931 TFA, a potent and selective agonist of the melanocortin 4 (MC4) receptor (IC50= nM) compared to the hMC3R (IC50=55 nM) and hMC5R (IC50= nM), is an analog of SHU 9119. This compound has demonstrated efficacy in reversing hemorrhagic shock and preventing multiple organ damage in vivo [2].