简介内容:SPR741 TFA (NAB741 TFA), a cationic peptide derived from polymyxin B, acts as a potentiator molecule that enhances the permeability of Gram-negative bacteria´s outer membrane, thereby facilitating the treatment of severe Gram-negative bacterial infections. This compound effectively inhibits multidrug-resistant Gram-negative bacteria and, when combined with antibiotics, broadens their spectrum of activity [1] [2].