简介内容:CTX-471, a fully human monoclonal antibody targeting CD137, exhibits binding affinity for CD137 across multiple species, including humans, cynomolgus macaques, and mice, with dissociation constant (Kd) values of 50 nM, 61 nM, and 748 nM, respectively. This compound is utilized in the study of immunomodulation and cancer research [1].