AOH1996；化合物AOH1996AOH1996T77520 - 上海陶术生物科技有限公司

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产品名称：AOH1996；化合物AOH1996AOH1996
产品型号：T77520
产品产地：中国大陆
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简介内容：AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase acts synergistically with DNA damaging agents to inhibit tumor ce

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原创作者：上海陶术生物科技有限公司

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