PTP1B/AKR1B1-IN-1；化合物 PTP1B/AKR1B1-IN-1PTP1B/AKR1B1-IN-1T78702

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产品名称：PTP1B/AKR1B1-IN-1；化合物 PTP1B/AKR1B1-IN-1PTP1B/AKR1B1-IN-1
产品型号：T78702
产品产地：中国大陆
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简介内容：PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s of μM for PTP1B and μM for AKR1B1. Additionally, it inhibits T-cell protein tyrosine phosphatase (TC-PTP) with an IC50 of 9 μM. This compound acts as an insulin-mimetic in murine myoblasts and diminishes AKR1B1-mediated sorbitol accumulation, contributing to the management of blood glucose levels and the inhibition of type 2 diab

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原创作者：上海陶术生物科技有限公司

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