PROTAC AR-NTD degrader 1；化合物 PROTAC AR-NTD degrader 1PROTAC AR-NTD degrader 1T78811

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产品名称：PROTAC AR-NTD degrader 1；化合物 PROTAC AR-NTD degrader 1PROTAC AR-NTD degrader 1
产品型号：T78811
产品产地：中国大陆
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简介内容：PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule belonging to the protein-targeting chimeras (PROTACs) that selectively targets the N-terminal domain (AR-NTD) of the Androgen Receptor variant AR-V7. By antagonizing AR-NTD, this compound effectively degrades AR-V7 protein and triggers apoptosis in prostate cancer (PC) cells, with degradation efficiencies in VCaP cells recorded at % (1 μM) and % (5 μM), as noted in reference [1].

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原创作者：上海陶术生物科技有限公司

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