DNL343；化合物 DNL343DNL343T78876 - 上海陶术生物科技有限公司

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产品名称：DNL343；化合物 DNL343DNL343
产品型号：T78876
产品产地：中国大陆
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简介内容：DNL343, a brain-penetrating eIF2B (eukaryotic initiation factor 2B) activator, suppresses the abnormal integrated stress response (ISR). By inhibiting ISR activity in the central nervous system (CNS), DNL343 ameliorates neurodegeneration and neuroinflammation. Additionally, it protects against motor dysfunction and premature death in eIF2B loss-of-function (LOF) mutant mice and demonstrates inhibitory potential for vanishing white matter disease (VWMD) characterized by eIF2B LOF and persistent I

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原创作者：上海陶术生物科技有限公司

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