简介内容:RET-IN-23 (compound 17) is a potent, orally active inhibitor of RET, displaying IC50 values of nM for RET-WT, nM for RET-CCDC6, nM for RET-V804L, nM for RET-V804M, and nM for RET-M918T. The compound demonstrates significant anti-tumor activity [1].