Antiproliferative agent-25；化合物 Antiproliferative agent-25Antiproliferative agent-25T79275

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产品名称：Antiproliferative agent-25；化合物 Antiproliferative agent-25Antiproliferative agent-25
产品型号：T79275
产品产地：中国大陆
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简介内容：Antiproliferative Agent-25 (Compound 3s4) is a selective PRMT5 inhibitor displaying an IC50 of μM. It elevates hnRNP E1 protein levels and forms hydrogen bond interactions with SAM and the E444 residue of PRMT5. This compound exhibits antiproliferative effects in A549 cells by inducing apoptosis and inhibiting migration, albeit it presents high clearance rates, with half-lives of minutes in human liver microsomes and minutes in rat liver microsomes [1].

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原创作者：上海陶术生物科技有限公司

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