MAO A/HSP90-IN-1；化合物 MAO A/HSP90-IN-1MAO A/HSP90-IN-1T79486

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产品名称：MAO A/HSP90-IN-1；化合物 MAO A/HSP90-IN-1MAO A/HSP90-IN-1
产品型号：T79486
产品产地：中国大陆
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简介内容：MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of μM in glioblastoma (GBM) GL26 cells and μM against HSP90α. This compound impairs the activities of MAO A, disrupts HSP90 binding, and downregulates both HER2 and phospho-Akt expressions, thereby inhibiting GBM growth. Additionally, it diminishes PD-L1 expression, thereby thwarting T cell activation and potential tumor immune evasion. MAO A/HSP90-IN-1 (4-b) is valuable for research into brain tumor

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原创作者：上海陶术生物科技有限公司

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