TRK-IN-24；化合物 TRK-IN-24TRK-IN-24T79706 - 上海陶术生物科技有限公司

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产品名称：TRK-IN-24；化合物 TRK-IN-24TRK-IN-24
产品型号：T79706
产品产地：中国大陆
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简介内容：TRK-IN-24 (compound 10g) is a selective inhibitor of Trk receptors, effectively targeting TRKA, TRKC, and mutant forms TRKA G595R, TRKA G667C, and TRKA F589L, with IC50 values of , , , , and nM, respectively. It demonstrates antitumor activity in BaF3-CD74-NTRK1 G595R and BaF3-CD74-NTRK1 G667C xenograft models and inhibits the proliferation of Ba/F3 cells expressing single mutants SF, GK, and xDFG, with an IC50 range of nM [1].

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原创作者：上海陶术生物科技有限公司

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