CARM1 degrader-1；化合物 CARM1 degrader-1CARM1 degrader-1T79741

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产品名称：CARM1 degrader-1；化合物 CARM1 degrader-1CARM1 degrader-1
产品型号：T79741
产品产地：中国大陆
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简介内容：PROTAC CARM1 degrader-1 (compound 3b) serves as a highly potent degrader (DC50= nM) of the co-activator associated arginine methyltransferase (CARM1). This compound facilitates the degradation of CARM1 via the VHL-proteasome pathway. By degrading CARM1, PROTAC CARM1 degrader-1 effectively reduces the methylation of its substrates, including poly(A)-binding protein PABP1 and BGR1-associated factor BAF155, subsequently inhibiting breast cancer cell migration [1].

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原创作者：上海陶术生物科技有限公司

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