PROTAC NSD3 degrader-1；化合物 PROTAC NSD3 degrader-1PROTAC NSD3 degrader-1T81377

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产品名称：PROTAC NSD3 degrader-1；化合物 PROTAC NSD3 degrader-1PROTAC NSD3 degrader-1
产品型号：T81377
产品产地：中国大陆
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简介内容：PROTAC NSD3 degrader-1 (compound 56) is a targeted degradation agent for the Nuclear receptor binding SET domain protein NSD3. It effectively induces the degradation of NSD3 in NCI-H1703 and A549 lung cancer cell lines, with DC50 values of and μM, respectively. Additionally, it hinders H3K36 methylation, triggers apoptosis, and arrests the cell cycle. Furthermore, PROTAC NSD3 degrader-1 diminishes the expression of NSD3-related genes, including CDC25A, ALDH1A1, and IGFBP.

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原创作者：上海陶术生物科技有限公司

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