简介内容：NSC15520, a small-molecule inhibitor of Replication Protein A (RPA), selectively targets the N-terminal DNA binding domain (DBD) of RPA, preventing its interaction with p53 and RAD9. Additionally, NSC15520 impedes the helix destabilization of duplex DNA (dsDNA) oligonucleotides, playing a role in processes such as DNA replication, repair, recombination, and the DNA damage response signaling pathway [1].
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