简介内容:AP-C6 is a potent inhibitor of guanosine 3´,5´-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 of . It inhibits human cGKII activity in vitro in a concentration-dependent manner and potentiates cAMP signaling through phosphodiesterase (PDE) inhibition [1].