GPX4 24；化合物 GPX4 24Phospholipid Hydroperoxide Glutathione Peroxidase 24|||PHGPx 24|||Glutathione PerT83780

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产品名称：GPX4 24；化合物 GPX4 24Phospholipid Hydroperoxide Glutathione Peroxidase 24|||PHGPx 24|||Glutathione Per
产品型号：T83780
产品产地：中国大陆
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简介内容：GPX4 24, a derivative of (1S,3R)-RSL3, acts as a potent inhibitor of glutathione peroxidase 4 (GPX4) through covalent binding in a concentration-dependent manner within 4T1 murine mammary carcinoma cells. This compound effectively induces ferroptosis in GPX4-dependent HT-1080 fibrosarcoma cells with an EC50 value of ?M. Additionally, at a dose of 200 mg/kg, GPX4 24 elevates malondialdehyde (MDA) levels in both kidney and plasma of mice, highlighting its impact on lipid peroxidation.

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名称: GPX4 24；化合物 GPX4 24

描述: 化合物 GPX4 24。

关键字: Phospholipid Hydroperoxide Glutathione Peroxidase 24 |PHGPx 24 |Glutathione Peroxidase 4 24；Phospholipid Hydroperoxide Glutathione Peroxidase 24 |PHGPx 24 |Glutathione Peroxidase 4 24 |

原创作者：上海陶术生物科技有限公司

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