简介内容：JQ1-FITC, a fluorescent BET bromodomain probe, exhibits high affinity binding to BRD4(BD1) and BRD4(BD2), with KD,app values of nM and nM respectively, as determined using GST-tagged BRD4 proteins in a CoraFluorTR-FRET assay; for BRD4(BD1), the value is nM in a fluorescence anisotropy assay. It has excitation and emission maxima (λ) of 495 nm and 525 nm.
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