TM2 TEAD inhibitor；化合物 TM2 TEAD inhibitorTM2 TEAD inhibitorT83951

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产品名称：TM2 TEAD inhibitor；化合物 TM2 TEAD inhibitorTM2 TEAD inhibitor
产品型号：T83951
产品产地：中国大陆
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简介内容：TM2 TEAD inhibitor, a robust and reversible inhibitor of the TEA domain transcription factor, presents dual inhibitory concentrations (IC50) of 38 nM for TEAD4 auto-palmitoylation and 156 nM for TEAD2 palmitoylation. It effectively blocks the TEAD-YAP association and their transcriptional activities, leading to significant antiproliferative effects in YAP-dependent cancer cell lines, both as a standalone agent and in combination with a MEK inhibitor. Additionally, it impedes YAP-dependent liver

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名称: TM2 TEAD inhibitor；化合物 TM2 TEAD inhibitor

描述: 化合物 TM2 TEAD inhibitor。

关键字: TM2 TEAD inhibitor |

原创作者：上海陶术生物科技有限公司

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